Institute of Molecular Biomedicine

IMBM is a research institute of the Faculty of Medicine at the Comenius University in Slovakia. We are located in Bratislava, both in the heart of the capital’s old town at Sasinkova 4, and in the Biomedical research center of the Slovak Academy of Sciences at Dubravská street 9.  The mission of IMBM is simple: to do (and enjoy doing) science. As of our staff, we have a vast range of educational background – from molecular biology, biophysics, biotechnology or physiology, up to medicine. While we believe that interdisciplinarity is a key scientific value. Furthermore, our partnerships extend to collaborating with clinicians and complementary research institutes all around the globe (Aachen, Gothenburg, New York, Boston, Hradec Králové…). This is a great enrichment to our  esearch. Of course, our institute is also home for many PhD students that are trained here in experimental and laboratory medicine, as well as undergraduate and graduate students that work on their bachelor/master/doctoral thesis with us. Moreover, our teaching takes place at the Faculty of Medicine and the Faculty of Natural  Sciences of the Comenius University. Ultimately, IMBM is an institute of open-minded people, scientists, who share their devotion to science. If you share this devotion with us, apply and come join us at the Institute of Molecular Biomedicine in Bratislava.

 

News

New article on type 2 diabetes mellitus research

Our head, Roman Gardlík, is a coauthor in a new publication, which was published in collaboration with several research teams. This study shows increased Na,K-ATPase activity and oxidative damage in the cerebellum of diabetic Zucker rats, suggesting potential compensatory mechanisms in this brain region despite systemic oxidative stress. Congratulations!

November 4, 2024

ESGCT 2024

At the European Society for Gene and Cell Therapy (ESGCT) conference, which took place on 22-25 October 2024 in Rome, Italy, associate professors Barbora Vlková and Peter Celec also participated. More information about the conference can be found here.

October 31, 2024

Research on NETs at the 14th Pediatric Nephrology Conference

Dr. Alexandra Gáal Kovalčíková and associate professor Michal Pastorek attended the 14th Conference on Pediatric Nephrology with international participation, which took place on October 18-19, 2024, in Tatranská Lomnica. In their presentations, both focused on the study of neutrophil extracellular traps (NETs). Dr. Gáal Kovalčíková presented her research on an animal model of crystal-induced chronic kidney disease, while associate professor Pastorek focused on the research of infectious and sterile inflammation. More detailed information about the conference can be found here.

October 28, 2024

Science

Projects

  • KEGA: KEGA 071UK-4/2022 Innovation of Practical Biomedical Research Courses for Doctoral Students
  • APVV: APVV-20-0472 Rapid identification of pathogens in sepsis patients using third-generation nanopore real-time sequencing
  • APVV: APVV-22-0554 Deoxyribonuclease 1l3 in the biology of extracellular DNA

Published papers

  • Altered sex differences related to food intake, hedonic preference, and FosB/deltaFosB expression within central neural circuit involved in homeostatic and hedonic food intake regulation in Shank3B mouse model of autism spectrum disorder
  • Oxidative Stress Markers and Na,K-ATPase Enzyme Kinetics Are Altered in the Cerebellum of Zucker Diabetic Fatty fa/fa Rats: A Comparison with Lean fa/+ and Wistar Rats
  • Shank3 deficiency alters midbrain GABAergic neuron morphology, GABAergic markers and synaptic activity in primary striatal neurons