Associate professor Sebekova in collaboration with colleagues from the Department of Pediatrics of Comenius University published a study investigating the relationship between plasma protein-bound advanced glycation end-products and their soluble receptors with bone health parameters in 102 girls with restrictive anorexia nervosa. They found that girls with anorexia nervosa had significantly higher levels of specific advanced glycation end-products compared to controls, and that elevated endogenous secretory receptor for advanced glycation end-products levels were associated with poorer bone quality, including lower bone mineral density at the hip and femoral neck. The findings suggest that monitoring the advanced glycation end-products could provide a novel clinical approach for assessing disease status and guiding personalized interventions to prevent long-term bone health consequences in patients with anorexia nervosa.