Several of our colleagues, led by doctor Barbara Tamášová, published an article in which they investigated how to better monitor early inflammation in ulcerative colitis (UC). In vivo chemiluminescence imaging is not reliable for detecting early inflammation, ex vivo chemiluminescence analysis and tests for hidden bleeding in stool have shown more promise in monitoring disease progression, chemiluminescence analysis more so, offering insights for improved non-invasive monitoring tools in UC research.