Congratulations! An article by our colleagues has been published in the prestigious journal Acta Neuropathologica Communications. A study using a mouse model of autism spectrum disorder demonstrates that acute liver injury induced by paracetamol can lead to long-term neuroinflammation, disruption of the blood-brain barrier, and behavioral deficits – effects that are more pronounced in genetically predisposed individuals. These findings support a preclinical framework for gene-environment interactions relevant to the vulnerability associated with autism spectrum disorder.